Vaccine manufacturers undertake rigorous clinical trials to validate their vaccine’s safety and efficacy to meet the standards for granting use authorization set by local regulatory agencies (e.g., the U.S. FDA). Even after approval for use, the vaccines are still continuously being monitored to ensure prompt and appropriate address of any new issues that arise.
Despite all the efforts in safety and quality control, individuals should carefully review the safety guidelines and recommendations from the vaccine manufacturers. Patients with known chronic (e.g., coronary artery disease, diabetes) or acute (e.g., fever or other flu like symptoms) health problems should always consult with a physician regarding their suitability of taking a specific vaccine. Moreover, patients should avoid inoculation if their immune system is already pre-occupied by undiagnosed asymptomatic health issues or acute illnesses.