Isoleucine is an essential branched-chain amino acid (BCAA), meaning the body cannot produce it—it must be obtained through diet. It plays critical roles in:
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Supporting muscle metabolism by promoting protein synthesis, reducing breakdown during exercise, and aiding recovery
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Regulating energy production through glucose metabolism (especially during fasting or intense activity)
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Maintaining metabolic balance as a precursor for liver glucose production and hemoglobin synthesis (oxygen transport)
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Enhancing immune function and wound healing through its role in cellular repair
Rich dietary sources of isoleucine include: meat, fish, poultry, eggs, dairy, legumes, nuts, and seeds.
Low isoleucine levels may contribute to muscle wasting, fatigue, unstable blood sugar, impaired recovery, and weakened immunity.