Tryptophan is an essential amino acid that serves as the biochemical precursor for critical neuroregulatory compounds. Its physiological significance includes:
Regulating neurological function as the sole precursor for serotonin (mood, appetite, cognition) and melatonin (sleep-wake cycles)
Supporting metabolic harmony through niacin (B3) synthesis for NAD+ production and cellular energy metabolism
Maintaining protein equilibrium as a rate-limiting component in protein biosynthesis
Modulating immune-nervous system crosstalk via kynurenine pathway metabolites
Optimal dietary sources: Turkey, chicken, salmon, eggs, cheese, pumpkin seeds, soybeans, oats
Low tryptophan levels may disrupt serotonin/melatonin production, potentially contributing to mood imbalances, sleep disturbances, and impaired niacin synthesis.